JenniSturges846: Created page with '''Serotonin syndrome signs''' Petulance, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiring, Shivering, Tremor, Cerebral status changes, Restless…'

JenniSturges846 — Thu, 08 Mar 2012 23:16:42 GMT

Created page with '''Serotonin syndrome signs''' Petulance, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiring, Shivering, Tremor, Cerebral status changes, Restless…'

New page

''Serotonin syndrome signs'''

Petulance, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiring, Shivering, Tremor, Cerebral status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Shaking, Pain in the abdomen, Diarrhea, Perspiring, Increased temperature, High blood pressure. Almost all these are symptoms of serotonin syndrome. Just about all will appear usually inside the first 24 hours following taking an overdose of serotonin drugs.
This signs are on mental processes level, autonomic level and SoNS degree.
Serotonin Toxidrome come often after o.d. of serotonin drugs and drug combination that increase synaptic serotonin. Drugs that tend to be understand to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Pep pill, Sibutramine, Cocaine, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Li, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Pep pill.
For the reason that serotonin syndrome it's not tested in the laboratory for diagnosis, symptoms tend to be the one that need observed. The best set of criteria to use to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome are as follows:
discontinuing drugs that produced the o.d. posible and drugs which can contribute
management of serotonin antagonist (eg. cyproheptadine) for cut cases of toxicity
for agitation, muscle tightness and seizure such as movements, benzodiazepines (Valium, Ativan)
Intra venous fluids
Because serotonin syndrome is not simple to diagnose, prevention is needed for any 5-hydroxytryptamine drugs combination that may lead to 5-hydroxytryptamine toxicity.

''Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642
Prator BC. Serotonin syndrome. J Neurosci Nurs. 2006 Apr;38(2):102-5.
Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.''

User:JenniSturges846 - Revision history

JenniSturges846: Created page with '''Serotonin syndrome signs''' Petulance, Craze, Loss of consciousness, Fits, Restlessness, Increased heart rate, Perspiring, Shivering, Tremor, Cerebral status changes, Restless…'