AndreasenDaniel295: Created page with '''Signs of serotonin syndrome''' Petulance, Delirium, Change, Fits, Restlessness, Increased middle rate, Perspiration, Chill, Tremor, Mental status changes, Restlessness, Increa…'

2012-03-08T21:29:04Z

Created page with '''Signs of serotonin syndrome''' Petulance, Delirium, Change, Fits, Restlessness, Increased middle rate, Perspiration, Chill, Tremor, Mental status changes, Restlessness, Increa…'

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''Signs of serotonin syndrome'''

Petulance, Delirium, Change, Fits, Restlessness, Increased middle rate, Perspiration, Chill, Tremor, Mental status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Moving, Pain in the stomach, Diarrhoea, Sweating, Increased temperature, Hypertension. Almost all these are signs or symptoms of serotonin syndrome. All will look usually in the first 24 hours after taking a great overdose of serotonin drugs.
This signs are on mental processes level, autonomic level and also SoNS level.
Serotonin Toxidrome appear frequently following overdose of serotonin drugs and also drug combination which increase synaptic serotonin. Drugs that tend to be understand to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Amphetamine, Sibutramine, Cocaine, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Lithium, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Pep pill.
Because serotonin syndrome it's not tested in the laboratory for diagnosis, symptoms tend to be the one that need seen. The greatest set of criteria to use to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome are because follows:
discontinuing drugs that created the overdose posible and also drugs that can lead
administration of serotonin antagonist (eg. cyproheptadine) for sever cases of toxicity
for agitation, muscle mass tightness and capture like movements, benzodiazepines (Valium, Ativan)
Intra venous liquids
Because serotonin syndrome is not simple to diagnose, protection is needed for any serotonin drugs combination that may lead to 5-hydroxytryptamine toxicity.

''Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642
Prator BC. Serotonin Syndrome. J Neurosci Nurs. 2006 Apr;38(2):102-5.
Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.''

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AndreasenDaniel295: Created page with '''Signs of serotonin syndrome''' Petulance, Delirium, Change, Fits, Restlessness, Increased middle rate, Perspiration, Chill, Tremor, Mental status changes, Restlessness, Increa…'